Glial origin of rapidly adhering amniotic fluid cells.

نویسندگان

  • P Aula
  • H von Koskull
  • K Teramo
  • O Karjalainen
  • I Virtanen
  • V P Lehto
  • D Dahl
چکیده

Rapidly adhering cells (RA cells) from the amniotic fluid of a pregnancy with fetal anencephaly were investigated by immunofluorescence assay with an antiserum against glial cells. After 24 hours' cultivation a high proportion of the cells showed positive glial-specific fluorescence, whereas no staining was seen in cells from samples of normal amniotic fluid. At the 24th week the mother was delivered of a stillborn infant with anencephaly. Immunofluorescence staining of RA cells with glial-specific antiserum may be used for the differential diagnosis of fetal abnormalities associated with a high alpha-fetoprotein concentration in amniotic fluid.

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عنوان ژورنال:
  • British medical journal

دوره 281 6253  شماره 

صفحات  -

تاریخ انتشار 1980